Discovery And Optimization Of A Series Of Pyrimidine Pde10 Inhibitors Through Fragment Screening, Structure-Based Design, And Parallel Synthesis
William D. Shipe, Pravien D. Abeywickrema,James C. Barrow, Rodney Bednar, Joseph Bruno, Victoria Cofre,Paul J. Coleman,Delphine Collin,Christopher D. Cox,Christine Fandozzi,Krista Getty, Sarah Huszar,Peter Hutson, Amanda Kemmerer, Raghu Krishnan,Wei Lemaire,Bennett Ma,Georgia Mcgaughey,Sanjeev Munshi, Shannon Nguyen, Mark B. Nolt,Sophie Parmentier-Batteur,Izzat T. Raheem, Steven S. Sharik,Sujata Sharma,Sean Smith, Cory Theberge,Jason Uslaner,Youwei Yan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2014）
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