Incorporation Of A Novel Nucleobase Allows Stable Oligonucleotide-Directed Triple Helix Formation At The Target Sequence Containing A Purine Center Dot Pyrimidine Interruption

D Guianvarc'H,R Benhida,Jl Fourrey,R Maurisse,Js Sun

CHEMICAL COMMUNICATIONS（2001）

Cited 66|Views0

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Abstract

Thermal denaturation experiments have established that an oligonucleotide incorporating the artificial nucleobase S, does form a stable triplex with a double stranded DNA which exhibits a pyrimidine interruption within the oligopurine sequence.

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