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Etiological characteristics of pediatric pulmonary infection and rational use of antibiotics

Shijiao Chen, Riming Fu, Ni Chen, Yuni Xu, Huijing Hu

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE(2020)

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摘要
Objective: To explore the etiological characteristics of pulmonary infection in pediatrics and the rational use of antibiotics. Methods: We retrospectively analyzed 768 of 2658 children with community-acquired pneumonia (CAP) and pathogen detection admitted from January 2018 to December 2019, and observed the irrational use of antibiotics. Results: The highest number of CAP cases was among children aged 0-1 year and the lowest in children aged 5-14 years (P<0.001). The morbidity of CAP was higher in winter than in the other three seasons (P<0.05). Pathogens were detected in 477 of 768 children (62.11%), and 188 of 477 children were coinfected with the two pathogens. Besides, the top three pathogens detected were respiratory syncytial virus, mycoplasma, and Haemophilus influenzae. The pathogen detection rate was higher in 5- to 14-year age group than in the other age groups (P<0.05). Antibiotics were used in 458 of 477 children with CAP (96.02%), with 43 (9.01%) cases of irrational drug use. Conclusion: We demonstrated the highest incidence of CAP in the winter, comparatively high detection rates of Haemophilus influenzae and respiratory syncytial virus, and high rate of irrational use of antibiotics. Therefore, it is necessary to strengthen the management and control of antibacterial agents in children with CAP.
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关键词
Children,community-acquired pneumonia,etiology,antibiotic,rational use of drugs
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