Optimization Of Supercritical Co2 Fluid Extraction Conditions Of Flavonoids From Spina Gleditsiae

In this work, supercritical CO2 fluid extraction method was used to extract the flavonoids from spina gleditsiae. we investigated the influence of four factors, namely entrainment dosage, extractive temperature, extractive pressure, and extractive time on the extraction of flavonoids. The optimum process conditions for the extraction were as follows: entrainment dosage of 37.5mL, extractive temperature of 45 degrees C, extractive pressure of 40Mpa, extractive time of 1.0h. The actual yield of flavonoids was 1.112%, which was close to the theoretical value of 1.116%.