A Giant Myxoid/Round-Cell Liposarcoma Of The Hip In A Pregnant Woman: A Case Report And Literature Review

Giant myxoid/round-cell liposarcoma (MRCL), a liposarcoma morphological variant, of the hip during pregnancy is rare. Low- and high-grade myxoid and round cells can be observed simultaneously, showing a progressive trend. Current treatments are limited; surgery is mainly used to reduce the tumor burden and relieve local symptoms. Here, we report a 36-year-old woman with a mass on the right hip present since trauma to this area and the right-side limb one year prior; the mass had been gradually growing for four months and increased significantly during pregnancy, accompanied by defecation difficulties. She underwent a resection of the mass; a histopathological examination confirmed MRCL. She chose to terminate the pregnancy and received radiotherapy (60 Gy). She was followed up for 37 months, with no signs of recurrence or metastasis. Here we report a rare case of a pregnant patient with giant MRCL of the hip. Preoperative biopsy should be performed; preoperative angiography and embolization can be conducted if the mass is large with a clear blood flow source. Although not reported previously, we applied this treatment and achieved satisfactory results, confirming its feasibility and effectiveness. This report provides new ideas for future treatment, though more cases are needed for further research.