New Emerging Molecules In Cancer Research Which Hold Promise In Current Era

Advancement in technologies and insights into biological systems has steered the increase in the arsenal of anticancer drugs in the last few decades. A systematic analysis of the 'OMICS' data abetted the emergence of novel drug targets in the areas of cell signaling, tumor microenvironment modulation and immune modulation. Innovative research is aimed at therapeutic targeting of cancer by addressing molecular anomalies of tumor cells in correlation with their ability to alter tumor and immune microenvironment for a favourable clinical outcome. In this chapter we describe advances in cancer therapies with an emphasis on drugs emerging through research ideas in basic tumor biology, key signaling kinases, tumor microenvironment modulation, cancer metabolism and immunomodulation with successful therapeutic translation.