Imparting Potential Antibacterial And Antifungal Activities To Water-Based Interior Paint Using Phytosynthesized Biocompatible Nanoparticles Of Silver As An Additive-A Green Approach

This chapter manifests an eco-friendly approach to synthesize silver nanoparticles and their use as a potential antibacterial and antifungal additive to water-based interior paint. Silver nanoparticles (AgNPs) were rapidly synthesized within 20 min using the leaves extract of Couroupita guianensis . UV–Vis spectroscopy, X-ray diffraction, Fourier transform–infrared spectroscopy, high-resolution transmission electron microscopy (HRTEM), and energy dispersive X-ray spectroscopy analysis were used to characterize the phytosynthesized AgNPs. UV–Vis spectrum analysis showed the surface plasmon peak at 415 nm. HRTEM analysis revealed the size of the AgNPs to be 5–15 nm. The biocompatibility of the phytosynthesized AgNPs was assessed in terms of percentage of cytotoxicity on mouse embryonic fibroblasts (NIH 3T3) and African green monkey kidney cells (Vero). This green nanohybrid coating formulation also offers manifold antimicrobial protection to surfaces by inhibiting the growth of bacteria like Escherichia coli, Staphylococcus aureus, Micrococcus luteus, Klebsiella pneumoniae, Bacillus subtilis, Pseudomonas aeruginosa , and the most virulent human pathogenic yeast the Candida spp., viz., Candida tropicalis , Candida krusei , Candida glabrata , Candida albicans .