Clinical Features And Outcomes In Acute Kidney Injury Patients Who Underwent Urgent Dialysis In A Regular Hemodialysis Unit

TURKISH JOURNAL OF NEPHROLOGY(2019)

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Abstract
Objective: An urgent hemodialysis (uHD) procedure is performed in acute kidney injury (AKI) with life-threatening complications. In this study, we aimed to investigate the clinical and laboratory findings that were associated with mortality in a regular HD unit.Materials and Methods: In total, 811. patients who underwent uHD were included in the study. The indications for uHD, demographic data, comorbidities, and pre- and post uHD laboratory results were obtained from patients' registry files. Clinical outcomes regarding the renal status after uHD, patient survival, and causes of mortality were evaluated.Results: The most common uHD indication was hypervolemia; 276 patients died in the follow-up period, and the most common cause of death was progression of underlying disorders. The most frequent renal outcome was dialysis dependency. Oliguria and hypotension during uHD were associated with an increased likelihood of mortality based on an age-adjusted analysis. According to a multivariate analysis, malignancy, presence of crackle, and prerenal AKI were independently associated with increased mortality.Conclusion: Due to high mortality in AKI, a prompt diagnosis and appropriate management of the patients are of paramount importance. Anticipation of the clinical risk factors associated with increased mortality may help in better stratification of patients at high risk.
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Key words
Acute kidney injury, comorbidity, hemodialysis, mortality, outcome
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