Vaccination Against Ticks

ECTOPARASITES: DRUG DISCOVERY AGAINST MOVING TARGETS(2018)

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摘要
Classically, tick infestation is controlled using acaricides that are administered as pour-ons, by dipping, or by spray race. Because of the continuous pressure of tick infestation and the decrease of active compound over time after administration, selection of relatively resistant ticks is a given. As a result of this, in all geographic areas resistant ticks have emerged, some of which are even multidrug resistant. As a consequence, there is also an upsurge in the prevalence of tick-transmitted diseases, which negatively impact the productivity of livestock. Vaccination against tick infestation would resolve these problems and does not select for drug-resistant tick strains.
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