Local Recurrence Of Malignant Fibrous Histiocytoma 18 Years After Hemipelvic Allograft Replacement: A Case Report And Review Of Literature

We report a rare case of very late local recurrence of malignant fibrous histiocytoma that occurred 18 years following initial treatment of the primary tumor wherein complete remission of the disease had been achieved. The patient had originally undergone a combined surgical mode of therapy immediately, and chemotherapy after the initial diagnosis, following which the patient was rendered disease-free. After a prolonged latent phase, the patient began to experience unexplained local symptoms. The patient was investigated at their local hospital where recurrence of the tumor was not initially considered as the cause of the presenting symptoms. After 18 years the patient was eventually referred back to the orthopedics department in Shanghai Tenth People's Hospital subsequent to the diagnosis of recurrent malignant fibrous histiocytoma being established. The patient has successfully undergone chemotherapy of the recurrent tumor and is receiving follow-up assessments at orthopedics department. We submit that this case highlights an under-appreciated need to remain vigilant for local tumor recurrence irrespective of the time of the initial diagnosis.