Correlation Between Platelet Parameters, Platelet/Lymphocyte Ratio And The Severity And Prognosis Of Chest Trauma Patients

Objective: To investigate the correlation between platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), platelet/lymphocyte ratio (PLR) and the severity and prognosis of chest trauma patients. Methods: A total of 84 chest trauma patients admitted to the Department of Traumatology Surgery in Yuyao People's Hospital were selected as observation group, and 84 healthy people were selected as control group. Platelet parameters and PLR levels of both groups were compared. Correlation between each indicator level of observation group and APACHE II score was analyzed. According to injury severity score (ISS), observation group was divided into non dangerous group (38 cases), dangerous group (29 cases) and extremely dangerous group (17 cases), and all the indicator levels of the three subgroups were compared. Also, observation group was divided into survival group (53 cases) and death group (31 cases) according to its survival condition. The levels of each indicator in both subgroups were compared, the prognostic indicators were analyzed by multivariate logistic regression, and the clinical value of each indicator in evaluating the prognosis of patients was analyzed by ROC curve. Results: Compared with healthy people, MPV and PDW levels in observation group were significantly increased, while PLR and PLT levels were significantly decreased (P<0.05). APACHE II score was positively correlated with MPV and PDW, and negatively correlated with PLR and PLT (P<0.05). The more severe the patient, the higher the MPV and PDW, and the lower the level of PLR and PLT (P<0.05). Compared with survival group, death group had higher MPV and PDW levels and lower PLR and PLT levels (P<0.05). The results of logistic regression analysis showed that PACHE II score, ISS, MPV, PDW, PLR, and PLT levels were the influencing factors for poor prognosis of chest trauma patients (P<0.05). ROC curve results showed that the area under the curve of MPV, PDW, PLT and PLR in evaluating the prognosis of chest trauma patients were all higher than 0.70 (P<0.05). Conclusion: Platelet parameters and PLR in chest trauma patients were closely related to the severity of the disease, and MPV, PDW, PLT and PLR had certain clinical value in evaluating the prognosis of chest trauma patients.