1 patients after death 2 Running head : Mean systemic pressure is altered by mechanical ventilation 3

1 Impact of positive pressure ventilation on mean systemic filling pressure in critically ill 1 patients after death 2 Running head: Mean systemic pressure is altered by mechanical ventilation 3 Xavier Repessé, Cyril Charron, Guillaume Geri, Alix Aubry, Alexis Paternot, Julien 4 Maizel, Michel Slama, Antoine Vieillard-Baron. 5 Author information 6 1 Assistance Publique-Hôpitaux de Paris, University Hospital Ambroise Paré, Intensive Care 7 Unit, Section Thorax-Vascular Disease-Abdomen-Metabolism, 92100 Boulogne-Billancourt, 8 France 9 2 University of Versailles Saint-Quentin en Yvelines, Faculty of Medicine Paris Ile-de-France 10 Ouest, 78280 Saint-Quentin en Yvelines, France 11 3 INSERM U-1018, CESP, Team 5 (EpReC, Renal and Cardiovascular Epidemiology), 12 UVSQ, 94807 Villejuif, France 13 4 Intensive Care Unit, University Hospital of Amiens, 80000 Amiens, France 14 5 Unité INSERM 1088, University of Picardie Jules Verne, Amiens, France 15 16 Address for correspondence and reprint requests 17 Prof. Antoine Vieillard-Baron, 18 Intensive Care Unit, Section Thorax-Vascular Disease-Abdomen-Metabolism, 19 University Hospital Ambroise Paré, 9, avenue Charles-de-Gaulle 92100 Boulogne-Billancourt 20 Email: antoine.vieillard-baron@aphp.fr, Phone: +33149095603 Fax: +33149095892 21 22 23 24 25 26 Articles in PresS. J Appl Physiol (March 30, 2017). doi:10.1152/japplphysiol.00958.2016