Effect Of Yogurt On Gastrointestinal Motility Of Dyspepsia Mice

With the development of the food industry and the improvement of the living standard, people's diet structure has changed gradually. Excessive diet with high calorie and high protein could cause dyspepsia. Aim of our study is to discuss the effect of yogurt on gastrointestinal motility of dyspepsia mice. Mice were randomly divided into four groups: normal group, model group, Chinese medical group (Drug group), and yogurt group. The mice of normal group were given ordinary feed, the rest of groups were given high protein and high calorie feed and administered through gastric intubation with 52% milk solution to establish dyspeptic model from day 1 to 4. the gastric emptying rate, intestinal propulsion rate, intestinal muscle tension, small intestinal contraction frequency and motilin were measured.Compared with the normal group, the gastric emptying rate, small intestinal propulsion rate, small intestine muscle tension, the small intestine contraction frequency and the motilin concentration were decreased in the model group, Compared with the model group, the intestine muscle tension in the yogurt group was increased, the difference has statistical significance(p<0.05), in addition, the gastric emptying rate in yogurt group was increased(p<0.05),the small intestine contraction frequency and the motilin of yogurt group were increased.Yogurt could improve gastrointestinal motility of dyspepsia mice.