Terbinafine In Tinea Capitis: Overview Of Efficacy And Safety From Randomized Duration-Finding Trials

Sf Friedlander,M Skerlev,J Lipozencic,R Aly, B Kraftchik, P Honig, Ak Gupta,La Wraith,Ng Gourmala,B Abrams,C Paul

SKIN AND ENVIRONMENT - PERCEPTION AND PROTECTION, VOLS 1 AND 2（2001）

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Abstract

Optimal terbinafine treatment durations were investigated in two separate double-blind trials in children with tinea capitis. Both studies found terbinafine to be safe, effective, and well tolerated. For infection with Trichophyton species., 2 to 4 weeks provided superior efficacy to 1 week. For Microsporum tinea capitis, 6 weeks was as effective as longer durations. These results suggest terbinafine should allow a reduction in recommended treatment duration compared to griseofulvin, the current standard therapy.

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