Expression Of Visfatin Influences The Development Of Coronary Artery Disease

Excessive intake of fatty substances resulted in an increased occurrence of coronary artery disease (CAD), an affecting people's life disease which has received widespread attentions. We found that patients with CAD had more adipose tissue than non-coronary artery disease in the artery surrounding. So, did increase of this localized fat play an active role? And whether it secretes more fat cells factor? In this study, by using immunohistochemistry, RT-PCR and western blotting methods, the expression of visfatin gene and protein between CAD and Non-CAD's adipose tissue surrounding coronary arteries and around the heart were compared. The purpose of the present study was to investigate the correlations between the expression of visfatin in coronary surrounding adipose tissue and coronary artery disease.