Association Between Post-Stroke Depression In Lacunar Stroke Patients And Rehospitalization

There are few studies that explore the impact of post-stroke depression (PSD) on the rehospitalization. The aim of the study was to investigate the relationship between PSD in lacunar stroke patients and rehospitalization at 1 year. A total of 526 lacunar stroke patients admitted to hospital were observed between Jul 2011 and Jul 2016. The patients were divided into PSD group and non-PSD group according to DSM-IV criteria. All patients were followed up for 12 months. The association between post-stroke depression in lacunar stroke patients and rehospitalization was estimated. Among 526 lacunar stroke patients, 102 patients (19.3%) were PSD. After adjusting for possible confounders, patients with PSD showed a significant increase in the risk of all-cause rehospitalization (OR = 2.18, 95% CI = 1.27-3.74), vascular rehospitalization (OR = 1.95, 95% CI = 1.09-3.50) and psychological rehospitalization (OR = 2.61, 95% CI = 1.41-4.85) at 1 year compared with the patients without PSD. Post-stroke depression in lacunar stroke patients may be associated with a higher risk of all-cause rehospitalization, vascular rehospitalization and psychological rehospitalization at 1 year.