Comparison Of Characteristics And Survival Between Incidental And Suspected Gallbladder Carcinoma

At present, the prognostic impact of incidentally discovered GBC (PI-GBC) and preoperative suspected GBC (PS-GBC) has not been widely studied. We enrolled 276 gallbladder carcinoma (GBC) patients upon whom surgical resection with curative intent was performed between January 2004 and December 2014. Of the 276 patients, 80 were identified with postoperative incidentally discovered gallbladder cancer (PI-GBC) and 196 were suspected with preoperative imaging (PS-GBC). Postoperative incidental gallbladder cancer (PI-GBC) was of lower T-stage (p<0.001), the lower presence of hepatic invasion (p<0.001) and lymph node metastasis (p<0.001), less intra-operative bleeding (p<0.001), less operative time (p=0.001), and less postoperative complication (5.0% vs. 17.9%, p=0.004). In the 276 GBC group, multivariate analysis revealed that only T stage, lymph node metastasis and tumour location were independent prognostic factors were independent prognostic factors. Postoperative incidental gallbladder cancer has a significantly lower degree malignant and better survival than preoperatively suspected GBC. However, incidental gallbladder cancer is not an independent factor that affects the prognosis. Incidental gallbladder cancer does not predict better prognosis, while it is worth the attention of clinicians.