Pseudomonas Aeruginosa Bacteriophage Pa1empty Set Requires Type Iv Pili For Infection And Shows Broad Bactericidal And Biofilm Removal Activities

We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1empty set has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1empty set may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.