Synthesis And Interfacial Properties Of Amphiphilic Beta-Cyclodextrins And Their Substitution At The O-6 Position With A Mono Bio-Recognisable Galactosyl Antenna
TETRAHEDRON(2005)
Abstract
The synthesis of a mono-galactosylated amphiphilic beta-cyclodextrin, in five steps from mono-6-azido-6-deoxy-beta-cyclodextrin, via coupling to a N-beta-D-galactopyranosylamino-antenna is described. Both characterization by electrospray mass spectrometry and NMR show the presence of only the mono-substituted product. The Langmuir isotherms of the final product and intermediates are described. (c) 2005 Elsevier Ltd. All rights reserved.
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Key words
amphiphilic cyclodextrin,galactosyl antenna,Langmuir isotherms
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