2D Image-Guided Cell Sorter and 3D Imaging Flow Cytometer
HIGH-SPEED BIOMEDICAL IMAGING AND SPECTROSCOPY V(2020)
摘要
Cell type classification and isolation according to imaging and spatial characteristics, beyond traditional fluorescently labeled biomarkers, enable the development of new biological insight and establishment of connections between phenotypical, morphological, and genomic cell information in normal and diseased states. Here we demonstrate a 2D image-guided cell sorter and a 3D imaging flow cytometer using fast scanning laser excitation sources. Both systems feature a cameraless design, which reconstructs cell images from the temporal readout of photomultiplier tubes.
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关键词
imaging flow cytometry,image-guided cell sorter,real-time cell sorting,3D cell imaging,AI-accelerated cell analysis
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