The Characteristics Of Uterine Leiomyoma And Metabolic Syndrome In The Multiparous Overweight Women In Northern Iran

Background: some Studies have shown that the incidence of Uterine Leiomyoma (U.L) is associated with obesity and hypertension as the components of metabolic syndrome.Therefore, authors aimed to investigate the relationship between incidence of U.L and their characteristics with metabolic syndrome and its components in women referring to Al-Zahra hospital in Rasht.Methods: This study was conducted in two groups (N=144) with and without U.L. Demographic, anthropometric, smoking, past medical history, serum lipids and blood glucose levels, U.L features including size, number, location of U.L and clinical symptoms were recorded. Data were analyzed in version21SPSS.Results: Results showed that there was no significant difference between the components of metabolic syndrome including waist circumference, systolic and diastolic blood pressure, fasting blood sugar and HDL levels in the groups (P> 0.05). There was no significant difference regarding the occurrence of metabolic syndrome in the groups (P> 0.05). However, individuals had U.L without metabolic syndrome were 28.9% asymptomatic, but in individuals with metabolic syndrome, this finding was decreased to 8.2 (P <0.001). Also the incidence of U.L (4.9%) in patients with metabolic syndrome was lower than those who didn't have metabolic syndrome (21.7%) (P = 0.014).Conclusion: The incidence of U.L in this study did not correlate with metabolic syndrome and its components, but those with metabolic syndrome were more likely to have abnormal uterine bleeding. The most common bleeding pattern was menometrorrhagia, and their U.L were less submucosal predominantly.