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Troubleshooting LC Separations of Biomolecules, Part 2: Passivation and Mobile-Phase Additives

Jordy J. Hsiao, Te-Wei Chu,Oscar G. Potter,Gregory O. Staples,Dwight R. Stoll

LC GC EUROPE（2020）

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Abstract
Bioinert and biocompatible liquid chromatography (LC) systems are becoming more commonplace in laboratories, but the majority of biomolecule separations still use LC systems composed primarily of stainless steel parts. Can passivation or mobile phase additives improve separations on these systems for metal-sensitive biomolecules?
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