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Synthesis Of New 3-(3-T-Butoxyl)Succinimidyl Monocyclic Beta-Lactams

Zhang Ping,Wang Ping,Li Yuan

CHINESE JOURNAL OF ORGANIC CHEMISTRY（2007）

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Abstract
3-(3-t-Butoxyl)succinimidyl acetyl chloride was obtained by a series of reactions starting from malic acid. 3-(3-t-Butoxyl)succinimidyl acetyl chloride reacted with Schiff bases 1a similar to 1h to yield 8 new 3-(3-t-butoxyl)succinimidyl monocyclic P-lactam derivatives 2a similar to 2h. The structures of the new compounds were confirmed by IR, H-1 NMR, MS spectra and elemental analysis.
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Key words
3-(3-t-butoxyl)succinimide acetyl chloride, schiff base, monocyclic beta-lactam
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