A Case Report And Literature Review Of Systemic Lupus Erythematosus With Sustained Elevated Serum Amylase And Lipase Levels

Systemic lupus erythematosus is a common autoimmune disease that can cause multiple organ damage, but the sustained increase of serum amylase and lipase without any corresponding clinical manifestations and imaging changes is relatively rare. We reported a case of systemic lupus erythematosus with pancreatic, salivary gland, central nervous system, skin, and thyroid involvement along with multiple organ damage accompanied by continuously increasing serum amylase and lipase levels. The patient was a young female who had suffered from the disease for about 13 years. After a relapse, her amylase and lipase levels continued to increase without any corresponding clinical manifestations or imaging changes. We followed up with the patient and summarized the changes in her serum amylase and lipase levels, and here we review the literature and analyze the reasons for the increases.