Analysis Of Clinical Features In 499 Psoriasis Patients With Metabolic Syndrome

Objective: To find the clinical features of psoriasis patients with metabolic syndrome (MS), its underlying etiology and pathogenesis, and the reaction between the severity of psoriasis and the onset of MS in patients with psoriasis. Method: Materials were obtained from 499 patients due to psoriasis vulgaris, 263 hospitalized patients due to allergic diseases and 340 individuals who received physical examination at the same stage from Sep. 1, 2011 to Dec. 31, 2017. Basic materials covered name, gender, age, body weight, height, BP, lipids, Glu and PASI score for patients with psoriasis. China Clinical Dermatology (2012, Zhao Bian) and diagnosis standards issued by the Diabetic Branch of Chinese Medical Association (2004) were referred to for diagnosis of psoriasis with MS respectively. Result: General materials were collected from 1102 individuals, of whom, 499 were patients with psoriasis, including 11 at mild (<= 2% BSA), 353 at moderate (2-10%) and 135 at severe degree (> 10%); 603 were included in the control group, of whom, 263 had allergic diseases and 340 were healthy. The study showed a relationship between psoriasis and MS as compared with healthy individuals and patients with allergic diseases, which was stronger in skin damage due to psoriasis worsened. Meanwhile, compared with patients with psoriasis only, psoriasis patients with MS demonstrated a longer LOS and high medical expenses on an average basis, which indicated the rising difficulty to treat psoriasis if it is accompanied by MS to a certain degree. Conclusion: Effective management is necessary to prevent MS in patients with psoriasis, especially those who are mild, while regular scientific popularization and screening for metabolic diseases are required in most severe cases of psoriasis.