Clinical And Histophatological Characterization Of Skin Pythiosis In A Donkey (Equus Asinus Africanus) Treated With Triamcinolone Acetonide Pythiosis Cutanea Equina

Cutaneous pythiosis (CP) is a chronic, granulomatous, pruritic and rapidly progressive disease that occurs in regions with temperatures ranging from temperate to hot climates, such as tropical and subtropical forests. Caused by Pythium insidiosum, a microorganism classified in the Phylum Pseudokingi, Class Oomycetes, Order Pythiales, Family Pythiaceae and Genus Pythium. It is known in Colombia as "equine espundia", in Brazil as "ferida brava, mal de los marshos and ferida de moda" and in other parts of the world as "granular dermatitis, leeches of Florida, fungus of the gulf coast, bursatee and pythiosis has been reported in several tropical and subtropical cuntries around the world, mainly in southern Brazil, Venezuela, Colombia, the United States of NorthAmerican, etc. Disabling injuries are located particularly in the limbs, mouth and chest, because they are the areas of greatest exposure to the microorganism, macroscopically, it is characterized by the presence of inflammatory ulcerated and granulomatous lesions, with irregular and crater-shaped edges, of different sizes, wet in most cases, may present pathways fistulous with occasional discharge of serosanguineous or purulent white-yellow material There are reports in the literature of various therapies with the aim of imine the etiological agent of the disease (P. insidiosum), improve tissue quality and promote tissue repair. The aim of the present study was to clinically characterize CP in a donkey (Equus asinus africanus) treated with triamcinolone. A descriptive, non-probabilistic study was conducted in convenience animals with presence of pyogranulomatous skin lesions compatible with Pythiosis, diagnosed with clinical examination and histopathological evaluations. After the definitive diagnosis, a treatment with intramuscular way of triamcinolone acetonide was established at a dose of 50 mg total for two applications with an interval of 15 days. The definitive diagnosis was based on the results of the histopathological tests, where it was found in the coloration with haematoxilin and eosine lesions compatible with pythiosis.