Tricyclic Benzomorphan Analogs By Intramolecular Oxa-Pictet-Spengler Reaction
TETRAHEDRON-ASYMMETRY(1993)
摘要
The key step in the regio- and stereoselective preparation of the benzomorphan analogues 9, 10a, 10b, 14 and 15 is an intramolecular Oxa-Pictet-Spengler reaction. Masked as an acetal the carbonyl component is connected via an amide to the 2-phenylethanol component (7, 12).
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