Phthalocyanine-Chalcone Conjugates

Fallia Aribi, Charlene Vey,Derya Topkaya,Sinem Tuncel Kostakoglu,Jeremie Fournier-Dit-Chabert,Sebile Isik Buyukeksi,Gokce Canan Taskin,Serkan Alpugan,Florian Albrieux,Ayse Gul Gurek,Melissa Cucca,Khalil Bennis,Devrim Atilla,Vefa Ahsen,Sylvie Ducki,Fabienne Dumoulin

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES（2016）

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摘要

A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone conjugates.

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关键词

phthalocyanine, chalcone, photodynamic therapy, photosensitizer, vascular disruption

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