Transient Spinal Cord Involvement In Reversible Splenial Lesion Syndrome: A Case Report

Reversible splenial lesion syndrome (RESLES) has largely been described in encephalitis/ encephalopathy. It is typically characterized by transient focal reversible symmetrical lesions, and show T2 hyperintensity with corresponding diffusion restriction and no contrast enhancement in the splenium of the corpus callosum (SCC) on magnetic resonance image (MRI), which can resolve completely or near completely within days or months. Previous cases have revealed the lesions could extend to other areas, such as the basal ganglia region, periventricular white matter, cerebral hemisphere, thalamus, cerebellum, the limbic system and brainstem. In the present case, transient lesions from the 1st to the 10th thoracic spinal cord were first reported in the syndrome in a patient with suspected tuberculous meningitis.