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Nanoparticles: Cancer Management Applications

CONCISE ENCYCLOPEDIA OF BIOMEDICAL POLYMERS AND POLYMERIC BIOMATERIALS, VOLS I-II(2018)

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Abstract
Nanoparticles (NP, 1-100 nm) find immense applications in research. Cancer is a deadly disease known to claim millions of lives globally wherein the main challenge revolves around its early detection, targeted delivery of anticancerous agents and targeted cell killing, overcoming drug resistance, and saving the healthy cells from toxic anticancer agents. Our current study includes the potential promising application of nanotechnology in the arena of cancer management, including NP in cancer research, management, and toxicity with special emphasis on polymer nanoparticles and their application in cancer management. Different types of polymeric nanoparticles together with engineered molecules such as antibodies, DNA, and receptors have been reported as efficient drug delivery devices and detection tools. The potential of nanoparticles in the detection, imaging, and targeting of cancer is advantageous over conventional methods. However, their toxicity and passage into tissues still raise concerns. Overcoming toxicity will enable these molecules to be important and promising tools in effective cancer management.
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