Detection And Awareness Of Chronic Renal Insufficiency And Related Complications At A Tertiary Care Hospital In China

Background: The prevalence of chronic renal insufficiency (CRI) has markedly increased in recent years worldwide, but the awareness remains low. In this cross-sectional study, we retrospectively investigated the detection and awareness of CRI and related complications at a tertiary care hospital in China. Methods: A total of 51,496 adult patients who were hospitalized at our hospital from October 2013 to December 2014 were included in this study. Demographics, clinical data, and laboratory data included urinary and hematologic parameters were collected. CRI was defined as estimated GFR (eGFR) <60 ml/min per 1.73 m(2), and patients with acute kidney injury were excluded. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) two-level race equation was used for reporting eGFR. Results: The subjects comprised 55.1% men and 44.9% women, the age was 68 (52-78) y. The overall prevalence of CRI was 4.1%. It was noted that there were about 64.8% CRI patients (excluded patients from nephrology department) being not diagnosed during their hospitalization. Among CRI patients, the prevalence of anemia, hypocalcaemia, hyperphosphatemia, and acidosis was 65.5%, 26.1%, 34.0% and 41.6% respectively, and the according prevalence increased significantly as renal function declined in patients without receiving dialysis. The total prevalence of hypertention and hyperkalemia was 54.5% and 9.9%, respectively, and rose by CKD stage. Conclusions: CRI and related complications were great burden in hospitalized patients, but the detection and awareness was still low. Future work is needed to organize a good management program to enable timely diagnosis and treatment of CRI and related complications.