CRISPR meets caspase
Nature Microbiology(2021)
摘要
Diverse CRISPR–Cas systems protect prokaryotes against invasive genetic elements like phages. A new study finds that evolution has fused a multi-subunit CRISPR complex into a single protein that cuts RNA and interacts with an ancillary caspase-like peptidase, which may trigger cell suicide.
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关键词
Bacterial host response,Phage biology,Life Sciences,general,Microbiology,Medical Microbiology,Parasitology,Infectious Diseases,Virology
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