Preproteins Couple the Intrinsic Dynamics of SecA to Its ATPase Cycle to Translocate Via a Catch and Release Mechanism

Srinath Krishnamurthy,Marios-Frantzeskos Sardis,Nikolaos Eleftheriadis,Katerina E. Chatzi,Jochem H. Smit,Konstantina Karathanou,Giorgos Gouridis,Athina G. Portaliou,Ana-Nicoleta Bondar,Spyridoula Karamanou,Anastassios Economou

Cell Reports（2022）

引用 8|浏览6

关键词

translocase,protein secretion,SecA,SecYEG channel,HDX-MS,smFRET,molecular dynamics,signal peptide,secretory clients,intrinsic dynamics,enzyme activation

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