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COVID-19-associated coagulopathy and unfavorable obstetric outcomes in the third trimester of pregnancy

Giulia E. Cetera, Francesco D'Ambrosi, Enrico Iurlaro, Nicola Cesano, Ilma F. Carbone, Stefano De Marinis, Enrico Ferrazzi

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS（2022）

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Abstract
Bleeding and clotting disorders occurring in patients with a SARS-CoV-2 infection have been defined as "COVID-19-associated coagulopathy" (CAC) [1]. Thrombosis caused by SARS-CoV-2 appears to occur in an indirect way, which includes all three components of Virchow's triad [2]. Initial CAC presents with elevation of D-dimer (DD) and increased serum fibrinogen, while prothrombin time, partial thromboplastin time, and platelet counts either change minimally or not at all [3].
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Key words
clotting disorders,COVID-19,COVID-19-associated coagulopathy,obstetric outcomes,pregnancy,SARS-CoV-2
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