The AlphaFold Database of Protein Structures: A Biologist’s Guide

Alessia David,Suhail Islam,Evgeny Tankhilevich,Michael J E Sternberg

Journal of Molecular Biology（2022）

引用 94|浏览19

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摘要

•AlphaFold, released the three-dimensional models (3D) of the human proteome.•Accurately and poorly modelled regions may be present within a single AlphaFold model.•The advantages, limitations and unsolved challenges of AlphaFold models are discussed.

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关键词

AlphaFold,human proteome,three-dimensional model,inter-domain accuracy

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