Application of musk heart-protection pills or musk heart-protection pill extract in preparing drugs for treating neurodegenerative diseases

user-5fe1a78c4c775e6ec07359f9(2019)

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摘要
The invention provides application of musk heart-protection pills or a musk heart-protection pill extract in preparing drugs for treating neurodegenerative diseases. It is proved through experiments that the musk heart-protection pills are prepared into various dosage forms by water dissolution, alcohol dissolution, artificial gastric juice treatment and other methods, the growth of PC12 nerves and the expression of neurofilament proteins can be significantly induced, and the mechanism of the musk heart-protection pills is related to the functions of promoting neurofilament protein promoters and activating protein kinase A (PKA) by the musk heart-protection pills; in addition, the neuroprotection function of the musk heart-protection pills is related to the effect of reducing gathering ofbeta-amyloid 1-42 (Abeta1-42) to inhibit immune inflammations of PC12 cells. The musk heart-protection pills can be used for preventing and treating the neurodegenerative diseases.
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关键词
Neuroprotection,Immune system,Pharmacology,Pill,Medicine,Heart protection,Neurofilament Proteins
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