Micro/nanoengineered technologies for human pluripotent stem cells maintenance and differentiation

Sajedeh Nasr Esfahani,Agnes M Resto Irizarry,Xufeng Xue, Samuel Byung-Deuk Lee,Yue Shao, Jiangping Fu

Nano Today（2021）

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摘要

•This review summarized micro/nanoengineered technologies for controlling human Pluripotent Stem Cell (hPSC) fate and function.•The role of biochemical and biomechanical cues, 3D biodegradable scaffolds, and microfluidic systems in determining hPSC fate is discussed.•The challenges faced by hPSC biologists and bioengineers are discussed.

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关键词

Human pluripotent stem cells (hPSCs),Micro/nanoengineering technologies,Biochemical cues,Biomechanical cues,Scaffolds,Microfluidics

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