Nanoparticles for local delivery of siRNA in lung therapy
Advanced Drug Delivery Reviews(2021)
Abstract
An overview of the application of natural and synthetic, non-viral vectors for oligonucleotide delivery into the lung is presented in this review, with a special focus on lung cancer. Due to the specificity of the respiratory tract, its structure and natural barriers, the administration of drugs (especially those based on nucleic acids) is a particular challenge.
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Key words
Drug delivery,Nanoparticles,Nucleic acids administration,Lung cancer therapy
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