Dual-Phase F-18-Florbetaben PET/CT Unsuspected Thalamic Infarction Mimicking Alzheimer Disease

Dual-phase amyloid PET is considered a useful protocol to study patients with cognitive impairment. Early-phase F-18-florbetaben PET/CT has been proposed as a surrogate of F-18-FDG PET/CT providing information related to regional brain perfusion. We report the case of a 61-year-old woman referred to the cognitive impairment unit for study, preliminary diagnosed as probable Alzheimer disease. The dual-phase F-18-florbetaben PET/CT was shown as the main finding, no uptake in the left anterior thalamus. Memory and language symptoms have been described as primary clinical features of anterior thalamic infarctions that could be confused with the main manifestations of Alzheimer disease.