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Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation

Ran Yan,Jie Ren,Jing Wen,Zheng Cao,Di Wu,Meng Qin,Duo Xu,Roxanne Castillo,Feifei Li,Fang Wang,Zhihua Gan,Chaoyong Liu,Ping Wei,Yunfeng Lu

ADVANCED MATERIALS（2022）

Cited 20|Views37
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Abstract
Ischemia-reperfusion injury (IRI) remains as a critical challenge for organ transplantation. Herein, an enzyme therapeutic based on superoxide dismutase and catalase for effective mitigation of IRI and pathogen-induced liver injury is reported, providing a therapeutic for organ transplantation and other diseases.
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Key words
antioxidants, enzyme therapeutics, ischemia-reperfusion injuries, organ transplantation, reactive oxygen species
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