Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation
ADVANCED MATERIALS(2022)
Abstract
Ischemia-reperfusion injury (IRI) remains as a critical challenge for organ transplantation. Herein, an enzyme therapeutic based on superoxide dismutase and catalase for effective mitigation of IRI and pathogen-induced liver injury is reported, providing a therapeutic for organ transplantation and other diseases.
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Key words
antioxidants, enzyme therapeutics, ischemia-reperfusion injuries, organ transplantation, reactive oxygen species
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