Metagenomics-driven rapid diagnosis of an imported fatal case of rare amoebic meningoencephalitis
JOURNAL OF TRAVEL MEDICINE(2022)
摘要
We identified Naegleria fowleri as the aetiologic agent from cerebrospinal fluid (CSF) of a patient with a travel history to Karachi. We demonstrate the benefit of metagenomics-based rapid diagnosis of primary amoebic meningoencephalitis (PAM) when routine clinical tests fail to provide a definitive diagnosis. We reconstructed the N. fowleri genome.
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关键词
Naegleria fowleri, primary ameobic meningoencephalitis, metagenomics, imported infectious diseases
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