Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection

International Journal of Infectious Diseases(2022)

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摘要
Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil.
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关键词
Zika virus,Congenital infection,Viral sequencing,Phylogenetic analysis
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