Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
International Journal of Infectious Diseases(2022)
摘要
Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil.
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关键词
Zika virus,Congenital infection,Viral sequencing,Phylogenetic analysis
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