A 30.3 fA/√Hz Biosensing Current Front-End With 139 dB Cross-Scale Dynamic Range

Da Ying,Chi-Yang Tseng,Ping-Wei Chen,Yu-Hwa Lo,Drew Hall

IEEE Transactions on Biomedical Circuits and Systems（2021）

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摘要

This paper presents an 8-channel array of low-noise (30.3 fA/√Hz) current sensing front-ends with on-chip microelectrode electrochemical sensors. The analog front-end (AFE) consists of a 1st-order continuous-time delta-sigma (CT ΔΣ) modulator that achieves 123 fA sensitivity over a 10 Hz bandwidth and 139 dB cross-scale dynamic range with a 2-bit programmable current reference. A digita...

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关键词

Sensors,Proteins,Modulation,Electrodes,Quantization (signal),Protein engineering,Bandwidth

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