Perineal cutaneous basal cell carcinomas in patients with familial seronegative coeliac disease: report of three cases
BRITISH JOURNAL OF DERMATOLOGY(2022)
摘要
The etiopathogenesis of basal cell carcinoma (BCC) arising in the perineum is unclear. We report BCC arising in the perineum of three longstanding untreated celiac disease (CD) patients. CD is an autoimmune enteropathy due to hypersensitivity to consumed gluten. Patients can present with gastrointestinal symptoms including diarrhea and weight loss, as well as fatigue, iron-deficiency anemia, vitamin D deficiency, depression, and unexplained hypocalcemia. As a result, CD often goes undiagnosed for many years before a diagnosis is made.
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