Enhancer RNA SLIT2 Inhibits Bone Metastasis of Breast Cancer Through Regulating P38 MAPK/c-Fos Signaling Pathway.

Peng Li,Zhiping Lin,Qianzheng Liu,Siyuan Chen, Xiang Gao,Weixiong Guo,Fan Gong,Jinsong Wei,Hao Lin

Frontiers in oncology（2021）

引用 13|浏览14

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摘要

Based on the co-expression network for bone metastasis of BRCA, we screened key eRNAs to explore a prognostic model in predicting the bone metastasis by bioinformatics analysis. Besides, we identified the potential regulatory signaling pathway of SLIT2 in BRCA bone metastasis, which provides a promising therapeutic strategy for metastasis of BRCA.

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关键词

MAPK/c-Fos pathway,SLIT2,bone metastasis,breast cancer,eRNAs

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