High-fat and combined high-fat-high-fructose diets impair episodic-like memory and decrease glutamate and glutamine in the hippocampus of adult mice.
Nutritional neuroscience(2022)
Abstract
These findings suggest that a possible adaptative long-term mechanism in the hippocampal neurotransmitters, and this possibility may underlie the episodic-like memory deficits in mice fed HFD and HFFrD.
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Key words
C57BL/6,GABA,Recognition memory,fat diet,glutamate,glutamine,high-fat–high-fructose diet,hippocampus
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