Eosinophilic fasciitis as a paraneoplastic syndrome in melanoma

Eosinophilic fasciitis (EF) is a rare sclerodermoid condition, characterized by acute-onset symmetric limb and trunk erythema, edema, induration, eventual fibrosis, and variable peripheral eosinophilia. EF is typically idiopathic; however, EF as a paraneoplastic condition has been recognized in a variety of hematologic disorders and solid organ tumors,1 and several cases have been initiated by immunotherapy.2 The association of EF with melanoma is rarely described.3