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Comparing Toxicity and Outcomes Between Twice-Daily (BID) vs. Pulsed Low-Dose Rate (PLDR) Radiotherapy (RT) for Reirradiation of Anorectal Cancers

A Pirlamarla, M Deng,J J Paly, H N Yankey,T Dougherty, E Dotan,J M Farma,J E Meyer

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

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Abstract
PLDR-RI of anorectal cancers appears to demonstrate a significant improvement in incidence and severity of toxicity compared to BID-RI. This is possible without compromising local progression-free survival. Increased utilization of PLDR-RI may be indicated.
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Key words
radiotherapy,toxicity,reirradiation,twice-daily,low-dose
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