Acute Toxicity in Patients Treated With Proton vs. Photon Chemoradiotherapy for Locally Advanced Head and Neck Cancer

K Kim, A Doucette, I Amaniera,B C Baumann,J Harton, P E Gabriel,N Mitra,J N Lukens, S D Swisher-McClure,A Lin,J M Metz,A P Wojcieszynski

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

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摘要

Concurrent chemoradiotherapy with proton therapy for head and neck cancers was associated with lower dose to nontarget structures and significantly reduced acute grade ≥3 toxicity and acute grade 2 oral cavity toxicity compared to photon therapy. Grade 2 skin toxicity favored photon therapy.

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