Comparison of NTCP Models Using Liver Function Obtained From Different Contrast Agent-Based DCE-MRI after SBRT in Hepatocellular Carcinoma

L Wei,M P Aryal,J J Simeth,K C Cuneo,M M Matuszak,T S Lawrence,R K Ten Haken, Y Cao,I El Naqa

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

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摘要

Functional maps showed steeper and lower dose for 50% complication compared with previous perfusion results. Considering its superiority to perfusion maps in representing liver "function", this may indicate a lower limit for normal liver dose or better dose distribution to preserve more liver function. The preliminary findings will be validated in a larger and independent cohort.

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